Tetanus results from contamination of a wound with bacteria
that produce a toxin which affects the nerves. The bacteria are found in soil
containing animal manure, so that any wound which may be exposed to dirt is a potential
entry point for tetanus. The wound may be very minor (such as a puncture wound
of the foot) or even forgotten; in newborn babies, infection usually occurs
through the umbilical cord.
Tetanus develops after a period of less than 2 weeks. It begins as difficulty
opening the mouth (lock-jaw) or sucking in babies. Stiffness of the jaw and neck
is followed by irritability and then severe spasms of the muscles of the abdomen
and back. Very severe cases may require artificial ventilation until the illness
has been effectively treated (with antitoxin and antibiotics).
As many as 90% of newborns with tetanus die, although the death rate is lower in
the general population (around 65%). Death usually results from breathing
problems. Patients who survive the first week are likely to recover.
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